
Dysport® has a wide FDA-approved dosing range, allowing for flexibility to customize subsequent doses based on patient response
Dysport is not interchangeable with other botulinum toxins, and the potency units are not the same.
Units of biological activity of Dysport cannot be compared to, or converted into, units of any other botulinum toxin product1
Recommended Doses-AULS
Clear dosing recommendations (AULS)
Dysport has clear dosing guidelines and a dosing app to help you inject approved muscles with appropriate doses1
- Dosing for upper limb spasticity: between Dysport 500 Units and Dysport 1000 Units divided among selected muscles at a given treatment session1
- The maximum recommended total dose (upper and lower limb combined) of Dysport for the treatment of spasticity in adults is Dysport 1500 Units1
- No more than 1 mL should generally be administered at any single injection site1
- Select dose based on muscles affected, severity of muscle spasticity, prior response, and adverse reaction history following treatment with Dysport1
- Retreatment should occur no sooner than 12 weeks after the previous injection1
Dysport has dosing recommendations for muscles in these common upper limb spasticity postures*1,3:
*Not actual patients.
Recommended Doses-ALLS
Clear dosing recommendations (ALLS)
Dysport has clear dosing guidelines and a dosing app to help you inject approved muscles with appropriate doses1
- Dosing for lower limb spasticity: between Dysport 1000 Units and Dysport 1500 Units divided among selected muscles at a given treatment session1
- The maximum recommended total dose (upper and lower limb combined) of Dysport for the treatment of spasticity in adults is Dysport 1500 Units1
- No more than 1 mL should generally be administered at any single injection site1
- Select dose based on muscles affected, severity of muscle spasticity, prior response, and adverse reaction history following treatment with Dysport1
- Retreatment, based on return of clinical symptoms, should occur no sooner than 12 weeks after the previous injection1
Dysport has dosing recommendations for muscles in these common lower limb spasticity postures*1,4:
*Not actual patients.
Recommended dilution options1
For adult spasticity
For other dilution options, refer to Table 1: Dilution Instructions for Dysport Vials (500 and 300 Units) in package insert Section 2.2: Preparation of Dysport Solution for Administration1
*Sterile, preservative-free 0.9% Sodium Chloride Injection, USP.
Dysport potency Units are not interchangeable with other botulinum toxin products.
Dilution & Reconstitution
Reconstitution and injection checklist
- Using a sterile syringe, needle, and aseptic technique, draw up the appropriate amount of diluent.*
- Insert the needle into the vial. The partial vacuum will begin to pull the diluent into the Dysport vial. Do not use the Dysport vial if no vacuum is observed.
- Swirl gently to dissolve. The reconstituted solution should be clear, colorless, and free of particulate matter.
- Draw the required patient dose of Dysport into a sterile syringe and dilute with additional diluent, if required, to achieve the final volume for injection.
- Expel any air bubbles in the syringe barrel. Remove the needle used to reconstitute the product and attach an appropriately sized new sterile needle to administer the injection.
- Inject into target muscle(s) within 24 hours of reconstitution. Dysport should be used for only one injection session and for only one patient after reconstitution.
*Sterile, preservative-free 0.9% Sodium Chloride Injection, USP.
Once reconstituted:
- Dysport should be used for only one injection session and for only one patient.
- Dysport should be stored in the original container, in a refrigerator at 2°C to 8°C (36°F to 46°F), protected from light for up to 24 hours. It must be discarded if not used within 24 hours.
- Do not freeze reconstituted Dysport.
- Discard the vial and needle in accordance with local regulations.
Reconstitution instructions are specific for the 300-Unit and 500-Unit vials.
Reconstituted Dysport is for intramuscular injection only.
Resources
Resources
Adult Spasticity Dosing & Dilution Webinar With Atul Patel, MD
Adult Spasticity Dosing & Dilution Webinar With Laxman Bahroo, MD
Training
Get Dysport Training With C.L.I.M.B.®

Whether you are new to adult spasticity management, thinking about trying Dysport, or looking for a refresher on administration, take your injection expertise to the next level with the C.L.I.M.B.® educational learning platform.
C.L.I.M.B. is a multitier learning continuum designed to accommodate physicians new to and experienced with botulinum toxin therapy. This educational curriculum is designed to help physicians across all levels improve their clinical skills involving the appropriate use of Dysport through online e-learning modules discussing some of the latest advances in the field for diagnosis, treatment and outcomes, on-demand peer-to-peer programs, and other educational resources. Be sure to visit CLIMB-training.com often to check for new content and updates.
E-learning modules currently available for adult spasticity.
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