What is lower limb spasticity in children?

Lower limb spasticity in children is a condition that causes increased muscle stiffness and involuntary muscle spasms.

Dysport can treat increased muscle stiffness in children 2 years of age and older with lower limb spasticity, which may help lessen symptoms.

Know the facts

Lower Limb Spasticity is a common problem for children with cerebral palsy.

Muscle spasms cause an abnormal position of the muscles.

As a result, children may often only be able to walk on their toes, because the stiff calf muscles make it hard for the ankle to flex, so feet point down and in.

This is called equinus foot deformity, and it is why children with lower limb spasticity often walk on their toes.

Treatment can help manage the condition and lessen symptoms, although there is no cure.

About LLS

Is your child (2 & older) experiencing the signs and symptoms of lower limb spasticity? You may notice the following:

Feet pointing down and in

Ankles that CAN'T flex

Tight calf muscles

Signs & symptoms

Treatment with Dysport

Dysport is injected into the affected muscles to help lessen your child’s symptoms.

Dysport is a type of medicine that is injected directly into affected muscles by a specialist. It helps to temporarily block signals from the brain that tell the affected muscles to contract or tighten, usually for months at a time.

Response to treatment may be different for each patient, so be sure to talk to your child’s doctor regularly during treatment.

Talk to your child’s doctor about your child’s condition and whether Dysport may be an option.

In the clinical trial, doctors measured each child (2 & older) treated with Dysport at Week 4 to see how well Dysport was working in 2 main ways:

  • Improvement in calf muscle stiffness (muscle tone)
  • The doctor’s overall impression of how each patient responded to treatment

After Dysport is injected into muscles, those muscles are weakened for up to 4 to 5½ months (16 to 22 weeks) or longer. This may help lessen your child’s symptoms.

Treatment with Dysport

  • Become a partner with your child’s doctor and treatment team by learning all the options to help your child
    • This may include working with a physical and/or occupational therapist to help loosen the affected area
  • Set goals but be open to making adjustments as needed

To find a doctor who injects Dysport, use our convenient Dysport Doctor Locator to help find a physician near you!


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Why Dysport?



What is the most important information I should know about Dysport?

Dysport may cause serious side effects, including problems breathing or swallowing and/or spread of toxin effects, that can be life threatening and death can happen as a complication. These problems can happen within hours, or days to weeks after an injection of Dysport.

  • Problems swallowing, breathing, or speaking. Treatment with Dysport can result in swallowing or breathing problems. People with pre-existing swallowing or breathing problems may be at greater risk following treatment with Dysport. Swallowing problems may last for several weeks; you may need a feeding tube to receive food or water. If swallowing problems are severe, food or liquids may go into your lungs.
  • Spread of toxin effects. The effects of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism which include: loss of strength and muscle weakness all over the body, double or blurred vision, and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing or swallowing. The risk of these symptoms is probably greatest in children treated for spasticity. These problems could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Call your doctor or get medical help right away if you experience these problems after treatment with Dysport.

Do not receive a Dysport injection if: you are allergic to Dysport or any of its ingredients, or cow’s milk protein; you had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®; or you have a skin infection at the planned injection site.

Before you receive a Dysport injection tell your doctor:

  • About all your medical conditions, including if you have a disease that affects your muscles and nerves (such as ALS or Lou Gehrig’s disease [amyotrophic lateral sclerosis], myasthenia gravis, or Lambert-Eaton syndrome). You may be at increased risk of serious side effects, including difficulty swallowing or breathing.
  • If you have or have had any of the following: a side effect from any botulinum toxin in the past; problems with breathing such as asthma or emphysema; swallowing; bleeding; diabetes; and slow heartbeat, or problems with your heart rate or rhythm.
  • If you have plans to have surgery, had surgery on your face, have weakness of your forehead muscles (trouble raising your eyebrows), drooping eyelids, or any other change in the way your face normally looks.
  • If you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Dysport can harm your unborn baby or if it passes into breast milk.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received Dysport in the past.

Especially tell your doctor if you have received any other injections of botulinum toxin in the last four months or ever; Myobloc®, Botox®, or Xeomin® (exactly which ones); an antibiotic recently by injection; or if you take muscle relaxants; allergy, cold or sleep medicine.

Most Common Side effects of Dysport in:

  • adults with upper limb spasticity include: urinary tract infection, muscle weakness, musculoskeletal pain, fall, depression, stuffy or runny nose and sore throat, and dizziness.
  • adults with lower limb spasticity include: muscle weakness, pain in your arms or legs, and fall.
  • people with cervical dystonia include: muscle weakness, dry mouth, feeling of tiredness, muscle pain, problems speaking, eye problems, difficulty swallowing, injection site pain, and headache.
  • children (2 to 17 years of age) with lower limb spasticity include: upper respiratory infection, stuffy or runny nose and sore throat, flu, cough, and fever.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Dysport. For more information, ask your doctor or pharmacist. You may report side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.


What is Dysport?

Dysport is a prescription medicine that is injected into muscles and used to treat:

  • cervical dystonia (CD) in adults
  • increased muscle stiffness in adults with spasticity
  • increased muscle stiffness in children 2 years of age and older with lower limb spasticity

It is not known whether Dysport is safe or effective in children under 2 years old for the treatment of lower limb spasticity; for treating other types of muscle spasms; or for treating cervical dystonia or upper limb spasticity in children under 18 years of age.


Please see Dysport Full Prescribing Information including Boxed Warning and Medication Guide.
Botox®, Xeomin®, and Myobloc® are registered trademarks of their respective owners.


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© 2019 Ipsen Biopharmaceuticals Inc. All rights reserved. March 2019 DYS-US-003338