Starting Dysport treatment

Before starting treatment:

  • Talk to your child’s doctor about treatment goals and the possible benefits and side effects your child may experience
  • Understand how spasticity is affecting your child now, before starting treatment

What to expect with Dysport treatment

Upper limb spasticity

In a clinical study, after the first injection, doctors measured the reduction in upper limb stiffness at 1½ months and recorded their overall impression of how each child responded to treatment. They recorded their overall impression again after 4 months.

 

Lower limb spasticity

In a clinical study, after the first injection, doctors measured the reduction in lower limb stiffness at 1 month and recorded their overall impression of how each child responded to treatment. They recorded their overall impression again after 3 months.

 

 

The next Dysport treatment should not be given sooner than 3 months after lower limb treatment, and it should not be given sooner than 4 months after upper limb treatment. Your healthcare professional will assess your child’s spasticity at each treatment session and may adjust the dose and muscles injected.

On injection day

Time
You should prepare to set aside enough time for your child’s Dysport appointment. You may spend anywhere from a few hours to the whole day in the doctor’s office. If your child is in school, he or she may miss some school or activities for the day.

Emotions
We understand that getting an injection is no fun for anyone. There are many things you can do to help minimize stress and make the day run as smoothly as possible. Consider bringing items that can make your child feel more comfortable, such as:

  • A favorite toy
  • Games
  • Puzzles

Many children may be able to resume normal activities shortly after their treatment.

After injection day

Results
For the first few days or weeks, you may not really see a difference in the stiffness of your child’s limb(s). In the studies, results were typically seen around 1 month after their treatment session. However, the time can vary for each child.

Side effects
Mild side effects such as soreness around the injection site, cough, and runny nose are common after injection with Dysport. Your child may also feel tired or fatigued afterward and want to rest. Keep an eye out for side effects, and call your child’s doctor immediately if they worsen or persist.

Additional therapy
Your child’s doctor will likely suggest your child continue with a physical therapy regimen as part of their spasticity management plan.

Tracking progress with Dysport

It is helpful to track your child’s progress between injection sessions with a notebook or calendar. You can also track the goals you discussed with your child and their doctor and revisit them at the follow-up appointment.

At each treatment session, the doctor will assess your child’s progress. Based on how your child is responding to treatment, the doctor may adjust the amount of Dysport they give your child. They may also change the muscles they inject.

Communicating changes and progress with your child’s doctor is very important. It helps them make adjustments so that treatment is tailored to your child.

Things to keep track of for your child’s doctor

  • How is your child responding to the injection?
  • Has their ability to move improved?
    • When did you start to see a response?
    • Has their ability to do everyday tasks improved?
  • Are they experiencing any side effects?
    • What are they?
    • How long do they last?
  • How long after their injection do you notice their symptoms of spasticity returning?

 

 

Annika was compensated for her appearance.

Annika, a child with lower limb spasticity who receives Dysport treatment

 

 

We are very pleased with how Annika is doing on Dysport. She moves smoother and faster…and she doesn’t have to work as hard….

Wendi, Annika’s mother

 

Plan ahead!

Remember, you may need time to schedule your next appointment, take time off from work or school, and/or arrange travel to and from the doctor’s office or clinic. Keep your child’s healthcare team informed about how he or she is doing and your plans.

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IMPORTANT SAFETY INFORMATION

What is the most important safety information I should know about Dysport?

Dysport may cause serious side effects, including problems breathing or swallowing and/or spread of toxin effects, that can be life threatening and death can happen as a complication. These problems can happen within hours, or days to weeks after an injection of Dysport.  

  • Problems swallowing, breathing, or speaking. Treatment with Dysport can result in swallowing or breathing problems. People with pre-existing swallowing or breathing problems may be at greater risk following treatment with Dysport. Swallowing problems may last for several weeks; you may need a feeding tube to receive food or water. If swallowing problems are severe, food or liquids may go into your lungs.
  • Spread of toxin effects. The effects of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism which include: loss of strength and muscle weakness all over the body, double or blurred vision, and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, and trouble breathing or swallowing. The risk of these symptoms is probably greatest in children treated for spasticity. These problems could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Call your doctor or get medical help right away if you experience these problems after treatment with Dysport.

Do not receive a Dysport injection if: you are allergic to Dysport or any of its ingredients, or cow’s milk protein; you had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®; or you have a skin infection at the planned injection site.

Before you receive a Dysport injection tell your doctor:

  • About all your medical conditions, including if you have a disease that affects your muscles and nerves (such as ALS or Lou Gehrig’s disease [amyotrophic lateral sclerosis], myasthenia gravis, or Lambert-Eaton syndrome). You may be at increased risk of serious side effects, including difficulty swallowing or breathing.
  • If you have or have had any of the following: a side effect from any botulinum toxin in the past; problems with breathing such as asthma or emphysema; swallowing; bleeding; diabetes; and slow heartbeat, or problems with your heart rate or rhythm.
  • If you have plans to have surgery, had surgery on your face, have weakness of your forehead muscles (trouble raising your eyebrows), drooping eyelids, or any other change in the way your face normally looks.
  • If you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if Dysport can harm your unborn baby or if it passes into breast milk.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received Dysport in the past.

Especially tell your doctor if you have received any other injections of botulinum toxin in the last four months or ever; Myobloc®, Botox®, or Xeomin® (exactly which ones); an antibiotic recently by injection; or if you take muscle relaxants; allergy, cold or sleep medicine.

Most Common Side effects of Dysport in:

  • adults with lower limb spasticity include: fall, muscle weakness, pain in your arms or legs.
  • adults with upper limb spasticity include: muscle weakness.
  • children (2 to 17 years of age) with upper limb spasticity include: upper respiratory infection and sore throat.
  • children (2 to 17 years of age) with lower limb spasticity include: upper respiratory infection, stuffy or runny nose and sore throat, cough, and fever.
  • adults with cervical dystonia include: muscle weakness, difficulty swallowing, dry mouth, injection site discomfort, tiredness, headache, muscle pain, problems speaking, injection site pain and eye problems.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Dysport. For more information, ask your doctor or pharmacist. You may report side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

What is Dysport?

Dysport is a prescription medicine that is injected into muscles and used to treat:

  • increased muscle stiffness in patients 2 years of age and older with upper and lower limb spasticity
  • cervical dystonia (CD) in adults

 

Please see full Prescribing Information including Medication Guide with Important Warning.

Botox, Xeomin, and Myobloc are registered trademarks of their respective owners.

© 2020 Ipsen Biopharmaceuticals Inc. All rights reserved. May 2020 DYS-US-004730